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Our SnAP Technology

SnAP (Site-specific novel Antibody Platform) technology is a powerful, yet broadly versatile, technology platform that transforms antibodies into a LEGO-like system … allowing for a broad range of payloads (cells, proteins, toxins, radioisotopes and much more) to be easily "snapped" on or off of an antibody, with unparalleled predictability, precision and control. 
A "LEGO-like" conjugation system 
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Binding pocket grafted into Fab​​

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  • Created through a handful of natural amino acid substitutions in the Fab of the antibody

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  • No negative effect on Ag binding

Meditope peptides

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  • Peptides (green) 'snap’ into pocket with specificity

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  • Non-covalent and covalent variants

Myriad of payloads

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  • Expanded universe of potential payloads, conjugated with ease

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  • Multiple, different payloads loaded onto a single meditope peptide

Endless possible combinations ...
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Radiopharmaceuticals

MDT-01: MeARC

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Cytokine Fusions

MDT-02: MeKine

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Bi-specifics

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ADCs

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CAR-T

And more!

© Meditope Biosciences

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